Image via CrunchBaseQ: Is there a TV remote that can work with just about ANY device? 

A: Logitech's Harmony remote control is the best, bar none. They have a whole slew of them, from $30 to HUNDREDS of dollars.

The simplest one, the Harmony 300, is programmable through your PC. Just get the exact make and model of the devices you want to control (the 300 controls 4 devices, usually TV, DVD, DVR, and Satellite, but you can choose which ones) Just go to MyHarmony.com, download the programmer (Firefox and IE only, sorry Chrome!) choose your devices, hit "sync", and voila, that's it.

It's the best $10 I've ever spent. You can get cheap "universal" remotes but why? This one is painless to program (just go to a PC, link the cable, and click a few buttons) and so far everything seem to work! ( a few buttons are not quite working as expected, but that's minor)